Sudden Onset of Brain Metastasis despite the Use of Vemurafenib for Another Metastatic Lesion in Malignant Melanoma Patients

Vemurafenib is an inhibitor of the BRAF mutation and has been approved by the Food and Drug Administration as a treatment option for patients with unresectable melanoma without brain metastasis. In the literature, vemurafenib has been reported to be also effective against brain metastasis. We encoun...

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Bibliographic Details

Published in:	Case Reports in Oncology
Main Authors:	Keisuke Imafuku, Koji Yoshino, Kei Yamaguchi, Satoshi Tsuboi, Kuniaki Ohara, Hiroo Hata
Format:	Article
Language:	English
Published:	Karger Publishers 2017-04-01
Subjects:	Malignant melanoma Vemurafenib Brain metastasis Drug resistance BRAF mutation Heterogeneous lesion LDH
Online Access:	http://www.karger.com/Article/FullText/461576