Patterns of genomic deletions in monkeypox virus during the 2022 outbreak in the United States

Abstract Poxviruses have a low overall rate of point mutations but are known to exhibit genomic duplications and deletions that can influence viral evolution. We examine the prevalence of large deletions in clade IIb monkeypox virus (MPXV) genomes during the global 2022 outbreak. We observe thirty-o...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Crystal M. Gigante, Daisy McGrath, Sophia Sukkestad, Hui Zhao, Mengfei Peng, Jade Takakuwa, Kimberly Wilkins, Vaughn Wicker, Audrey Matheny, Theodora Khan, Whitni B. Davidson, Mili Sheth, Alex Burgin, Julie Hand, Gillian Richardson, Danielle Haydel, Mark Burroughs, Jasmine Padilla, Justin S. Lee, Dhwani Batra, Ethan E. Hetrick, Dakota T. Howard, Kyle O’Connell, Jessica L. Rowell, Shatavia Morrison, Sarah Gillani, Michelle Lee, Anil Mangla, David Blythe, Robert Myers, Lynsey Kovar, Matthew H. Seabolt, Michael R. Weigand, Panayampalli S. Satheshkumar, Andrea M. McCollum, Christina L. Hutson, Yu Li
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Online Access:	https://doi.org/10.1038/s41467-025-64003-y