Mesencephalic astrocyte-derived neurotrophic factor is secreted from interferon-γ-activated tumor cells through ER calcium depletion.

The most successful immunotherapeutic agents are blocking antibodies to either programmed cell death-1 (PD-1), an inhibitory receptor expressed on T lymphocytes, or to its ligand, programmed cell death-ligand 1 (PD-L1). Nevertheless, many patients do not respond, and additional approaches, specifica...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Michael Peled, Tali H Bar-Lev, Efrosiniia Talalai, Haggar Zoë Aspitz, Inbal Daniel-Meshulam, Jair Bar, Iris Kamer, Efrat Ofek, Adam Mor, Amir Onn
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0250178