Immunological signatures unveiled by integrative systems vaccinology characterization of dengue vaccination trials and natural infection

IntroductionDengue virus infection is a global health problem lacking specific therapy, requiring an improved understanding of DENV immunity and vaccine responses. Considering the recent emerging of new dengue vaccines, here we performed an integrative systems vaccinology characterization of molecul...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Desirée Rodrigues Plaça, Dennyson Leandro M. Fonseca, Alexandre H. C. Marques, Shahab Zaki Pour, Júlia Nakanishi Usuda, Gabriela Crispim Baiocchi, Caroline Aliane de Souza Prado, Ranieri Coelho Salgado, Igor Salerno Filgueiras, Paula Paccielli Freire, Vanderson Rocha, Niels Olsen Saraiva Camara, Rusan Catar, Guido Moll, Igor Jurisica, Vera Lúcia Garcia Calich, Lasse M. Giil, Laura Rivino, Hans D. Ochs, Gustavo Cabral-Miranda, Lena F. Schimke, Otavio Cabral-Marques
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	dengue vaccine transcriptional signature immune response systems vaccinology
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1282754/full