CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment

Abstract Detecting genetic variants enables risk factor identification, disease screening, and initiation of preventative therapeutics. However, current methods, relying on hybridization or sequencing, are unsuitable for point-of-care settings. In contrast, CRISPR-based-diagnostics offer high sensit...

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Bibliographic Details

Published in:	EMBO Molecular Medicine
Main Authors:	Robert Greensmith, Isadora T Lape, Cristian V Riella, Alexander J Schubert, Jakob J Metzger, Anand S Dighe, Xiao Tan, Bernhard Hemmer, Josefine Rau, Sarah Wendlinger, Nora Diederich, Anja Schütz, Leonardo V Riella, Michael M Kaminski
Format:	Article
Language:	English
Published:	Springer Nature 2024-09-01
Subjects:	Biomarkers Diagnostics CRISPR-based-genotyping APOL1 Kidney Disease
Online Access:	https://doi.org/10.1038/s44321-024-00126-x