Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate

Abstract Background Patients with chronic kidney disease (CKD) have a high prevalence of cerebrovascular disease and cognitive impairment. The objective was to analyse whether plasma concentrations of neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP) and phosphorylated Tau231 (...

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Bibliographic Details

Published in:	BMC Nephrology
Main Authors:	Torunn Axelsson, Henrik Zetterberg, Kaj Blennow, Burak Arslan, Nicholas J. Ashton, Markus Axelsson, Maria K. Svensson, Aso Saeed, Gregor Guron
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Chronic kidney disease Glial fibrillary acidic protein Glomerular filtration rate Neurofilament light Tau
Online Access:	https://doi.org/10.1186/s12882-025-04130-2