Transcriptomes of Clusterin- and S100B-transfected neuronal cells elucidate protective mechanisms against hypoxia and oxidative stress in the hooded seal (Cystophora cristata) brain

Abstract Background The hooded seal (Cystophora cristata) exhibits impressive diving skills and can tolerate extended durations of asphyxia, hypoxia and oxidative stress, without suffering from irreversible neuronal damage. Thus, when exposed to hypoxia in vitro, neurons of fresh cortical and hippoc...

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Bibliographic Details
Published in:BMC Neuroscience
Main Authors: Gerrit A. Martens, Cornelia Geßner, Carina Osterhof, Thomas Hankeln, Thorsten Burmester
Format: Article
Language:English
Published: BMC 2022-10-01
Subjects:
Clusterin
S100B
Hypoxia
Oxidative stress
Transcriptome
Neurons
Online Access:https://doi.org/10.1186/s12868-022-00744-6

Internet

https://doi.org/10.1186/s12868-022-00744-6

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