Microglia Depletion from Primary Glial Cultures Enables to Accurately Address the Immune Response of Astrocytes

Astrocytes are the most abundant cells in the CNS parenchyma and play an essential role in several brain functions, such as the fine-tuning of synaptic transmission, glutamate uptake and the modulation of immune responses, among others. Much of the knowledge on the biology of astrocytes has come fro...

Full description

Bibliographic Details

Published in:	Biomolecules
Main Authors:	Mariana Van Zeller, Ana M. Sebastião, Cláudia A. Valente
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	mixed glial cultures astrocytes microglia CSF-1R PLX-3397 C3
Online Access:	https://www.mdpi.com/2218-273X/12/5/666