Predictive value of tissue eosinophilia for dupilumab response in chronic rhinosinusitis with nasal polyps: A retrospective monocentric study

Objective: To evaluate the predictive value of baseline tissue eosinophilic infiltration (cells/high-power field [HPF]) in determining clinical response to dupilumab in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: This retrospective, single-center observational study inc...

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Bibliographic Details

Published in:	World Allergy Organization Journal
Main Authors:	Gian Marco Pace, MD, Giulia Mari, MD, Francesco Giombi, MD, Michele Cerasuolo, MD, Camilla Zimello, MD, Luca Cerri, MD, Giorgio Walter Canonica, MD, Enrico Heffler, MD PhD, Giovanni Paoletti, MD, Francesca Puggioni, MD, Barbara Fiamengo, MD, Silvia Uccella, MD, Giuseppe Mercante, MD, Giuseppe Spriano, MD, Luca Malvezzi, MD
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	Chronic rhinosinusitis Nasal polyps Dupilumab Tissue eosinophilia Patient-reported outcome
Online Access:	http://www.sciencedirect.com/science/article/pii/S1939455125001061