A contribution to the study of hydrophobicity (lipophilicity) of bile acids with an emphasis on oxo derivatives of 5β-cholanoic acid

Due to their promotory action on the transport of some drugs through various membranes (lipophilic barriers), oxo derivatives of bile acids have recently been increasingly used in biopharmacy. These compounds exhibit also a lower membranolytic (toxic) activity than their hydroxy analogues. Becaus...

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Bibliographic Details

Published in:	Hemijska Industrija
Main Authors:	Poša Mihalj, Rašeta Milena, Kuhajda Ksenija
Format:	Article
Language:	English
Published:	Association of Chemical Engineers of Serbia 2011-01-01
Subjects:	bile acid oxo derivatives hydrophobicity (lipophilicity) retention constant - RM0
Online Access:	http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1000071P.pdf