The Association of the COMT V158M Polymorphism with Endometrial/Ovarian Cancer in HNPCC Families Adhering to the Amsterdam Criteria
<p>Abstract</p> <p>Catechol-O-methyltransferase (COMT) is vital for the conjugation of catechol estrogens that are produced during oestrogen metabolism. The efficiency of this process varies due to a polymorphism in COMT, which changes valine to methionine (V158M). The Met genotype...
| الحاوية / القاعدة: | Hereditary Cancer in Clinical Practice |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
BMC
2006-05-01
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | http://www.hccpjournal.com/content/4/2/94 |
