Identification and verification of a polyamine metabolism-related gene signature for predicting prognosis and immune infiltration in osteosarcoma

Abstract Background Although an established correlation exists between tumor cell proliferation and elevated polyamine levels, research on polyamine metabolism in osteosarcoma (OS) remains limited. This study aimed to identify polyamine metabolism-related genes (PMRGs) associated with OS prognosis a...

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Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Authors: Shuo Qiu, Chen Tan, Dongdong Cheng, Qingcheng Yang
Format: Article
Language:English
Published: BMC 2025-05-01
Subjects:
Osteosarcoma
Polyamine metabolism
Prognostic genes
Immune infiltration
Risk model
Online Access:https://doi.org/10.1186/s13018-025-05716-0

Internet

https://doi.org/10.1186/s13018-025-05716-0

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