Deficiencies in corin and atrial natriuretic peptide-mediated signaling impair endochondral ossification in bone development

Abstract Corin is a protease that activates atrial natriuretic peptide (ANP), a hormone in cardiovascular homeostasis. Structurally, ANP is similar to C-type natriuretic peptide (CNP) crucial in bone development. Here, we examine the role of corin and ANP in chondrocyte differentiation and bone form...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Zibin Zhou, Xiaoyu Mao, Chun Jiang, Wenguo Li, Tiantian Zhou, Meng Liu, Shijin Sun, Mengting Wang, Ningzheng Dong, Qingyu Wu, Haibin Zhou
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Online Access:	https://doi.org/10.1038/s42003-024-07077-6