PICH deficiency limits the progression of MYC-induced B-cell lymphoma

Abstract Plk1-interacting checkpoint helicase (PICH) is a DNA translocase involved in resolving ultrafine anaphase DNA bridges and, therefore, is important to safeguard chromosome segregation and stability. PICH is overexpressed in various human cancers, particularly in lymphomas such as Burkitt lym...

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Bibliographic Details

Published in:	Blood Cancer Journal
Main Authors:	María Castejón-Griñán, Eliene Albers, Lucía Simón-Carrasco, Paula Aguilera, Mauro Sbroggio, David Pladevall-Morera, Andreas Ingham, Ernest Lim, Alba Guillen-Benitez, Elena Pietrini, Michael Lisby, Ian D. Hickson, Andres J. Lopez-Contreras
Format:	Article
Language:	English
Published:	Nature Publishing Group 2024-01-01
Online Access:	https://doi.org/10.1038/s41408-024-00979-y