Assessment of Biological Properties of Recombinant Lumpy Skin Disease Viruses with Deletions of Immunomodulatory Genes

Rational design of capripoxvirus-based vaccine vectors can be achieved by knockout of immunomodulatory genes. In this study, the effect of knockout of the immunomodulatory genes LSDV005, LSDV008 and LSDV066 on the replication of Lumpy skin disease virus in cell cultures and the immune response to an...

Full description

Bibliographic Details

Published in:	Viruses
Main Authors:	Aisha Issabek, Arailym Bopi, Nurlan Kozhabergenov, Bermet Khudaibergenova, Kulyaisan Sultankulova, Olga Chervyakova
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	lumpy skin disease virus immunomodulatory gene vaccine vector
Online Access:	https://www.mdpi.com/1999-4915/17/10/1390