A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes

Abstract We manufactured a novel type of lipid‐coated superparamagnetic nanoparticles that allow for a rapid isolation of plasma membranes (PMs), enabling high‐resolution proteomic, glycomic and lipidomic analyses of the cell surface. We used this technology to characterize the effects of presenilin...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Deepak B Thimiri Govinda Raj, Bart Ghesquière, Arun Kumar Tharkeshwar, Katrijn Coen, Rita Derua, Dieter Vanderschaeghe, Evelien Rysman, Murali Bagadi, Pieter Baatsen, Bart De Strooper, Etienne Waelkens, Gustaaf Borghs, Nico Callewaert, Johan Swinnen, Kris Gevaert, Wim Annaert
Format:	Article
Language:	English
Published:	Springer Nature 2011-10-01
Subjects:	eukaryotic cell systems glycomics lipidomics presenilin, proteomics
Online Access:	https://doi.org/10.1038/msb.2011.74