Chronic stress is associated with pain precipitation and elevation in DeltaFosb expression

A number of acute or repeated stimuli can induce expression of DeltaFosB (ΔFosB), a transcription factor derived from the fosB gene (an osteosarcoma viral oncogene) via alternative splicing. ΔFosB protein is currently viewed as a 'molecular switch' to repeated stimuli that gradually conver...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Hang eWang, Xinrong eTao, Si-Ting eHuang, Liang eWu, Hui-Li eTang, Ying eSong, Gongliang eZhang, Yong-Mei eZhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-05-01
Subjects:	Pain Medial prefrontal cortex western blot deltaFosB ΔFosB
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00138/full