Longitudinal associations between amyloid and symptoms of depression and anxiety in subjective cognitive decline: the impact of personality characteristics

IntroductionDepressive/anxiety symptoms are common in subjective cognitive decline (SCD) and may relate to Alzheimer’s pathology, potentially modulated by personality characteristics.MethodsDepressive/anxiety symptoms were assessed over 4 ± 2 years in 329 SCD (88 amyloid-positive/241 amyloid-negativ...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Calvin Trieu, Mardou S. S. A. van Leeuwenstijn, Lisa-Marie Schlüter, Jarith L. Ebenau, Inge M. W. Verberk, Sietske A. M. Sikkes, Sander C. J. Verfaillie, Elsmarieke van de Giessen, Charlotte E. Teunissen, Wiesje M. van der Flier, Argonde C. van Harten
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	Alzheimer’s disease depression anxiety subjective cognitive decline neuroticism somatization
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1572174/full