Efficacy and Safety Evaluation of Intrathecal Pemetrexed in EGFR-mutated NSCLC Patients 
with Leptomeningeal Metastases

Background and objective The incidence of leptomeningeal metastasis (LM) in patients with advanced non-small cell lung cancer (NSCLC) is increasing gradually. However, it poses therapeutic challenges due to limited effective interventions. Intrathecal Pemetrexed (IP) holds broad application prospect...

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Bibliographic Details

Published in:	Chinese Journal of Lung Cancer
Main Authors:	Tianli ZHANG, Xin CHEN, Cheng JIANG, Yongjuan LIN, Yu XIE, Huiying LI, Zhenyu YIN, Tingting YU
Format:	Article
Language:	Chinese
Published:	Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2025-08-01
Subjects:	lung neoplasms leptomeningeal metastasis epidermal growth factor receptor intrathecal chemotherapy pemetrexed
Online Access:	http://dx.doi.org/10.3779/j.issn.1009-3419.2025.106.23