Small molecules as ligands in the tuning of immune regulatory receptors

Professional antigen-presenting cells (APCs) represent a crucial link between the innate and the adaptive immune response. APCs express specific surface receptors which are primarily involved in “non-self” and/or “self” ligand recognition. Upon ligand binding, these receptors can trigger cell signal...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Laura Fioretto, Marcello Ziaco, Genoveffa Nuzzo, Federica Albiani, Marisa Saponaro, Dalila Carbone, Giusi Barra, Mario dell’Isola, Olimpia Follero, Nunzia Esercizio, Daniela Castiglia, Giuliana d’Ippolito, Carmela Gallo, Angelo Fontana, Emiliano Manzo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	small ligands C-type lectin receptor immunoglobulin receptors innate immune system immunology
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1648691/full