The Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin

Abstract Background The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported to affect cancer cells but not non-malignant cells, rendering prodigiosin a promising lead c...

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Bibliographic Details

Published in:	Cell Communication and Signaling
Main Authors:	Lena Berning, Thomas Lenz, Ann Kathrin Bergmann, Gereon Poschmann, Hannah U. C. Brass, David Schlütermann, Annabelle Friedrich, María José Mendiburo, Céline David, Seda Akgün, Jörg Pietruszka, Kai Stühler, Björn Stork
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	Prodigiosin Golgi apparatus Natural compound Autophagy Target identification
Online Access:	https://doi.org/10.1186/s12964-023-01275-1