Generation of a biallelic NRAP-knockout mutant from a human iPSC line

Cardiomyopathies, a leading cause of mortality, are associated with dysfunctional intercalated discs, which connect neighbouring cardiomyocytes and ensure proper contractility. In human cardiac diseases, loss-of-function mutations of the intercalated disc-associated protein Nebulin-Related Anchoring...

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Bibliographic Details
Published in:Stem Cell Research
Main Authors: Janice Raabe, Vanessa Lewandowski, Sigrid Fuchs, Alexandra Hammerschmidt, Angelika Piasecki, Ellen Orthey, Elisabeth Krämer, Elisabeth Ehler, Friederike Cuello
Format: Article
Language:English
Published: Elsevier 2025-10-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506125001795

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http://www.sciencedirect.com/science/article/pii/S1873506125001795

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