ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke

Abstract Background Inflammatory response has been recognized as a pivotal pathophysiological process during cerebral ischemia. ChemR23 signaling is involved in the pathophysiology of various inflammatory diseases. Nevertheless, the role of ChemR23 signaling in ischemic stroke remains largely unknow...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Lan Liu, Jiawei Zhang, Kaili Lu, Yaxuan Zhang, Xiaofeng Xu, Jiangshan Deng, Xiaojie Zhang, Haibing Zhang, Yuwu Zhao, Xiuzhe Wang
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Stroke ChemR23 Pyroptosis NLRP3 inflammasome Neuron
Online Access:	https://doi.org/10.1186/s12967-023-04813-0