Modulation of Inherent Niches in 3D Multicellular MSC Spheroids Reconfigures Metabolism and Enhances Therapeutic Potential

Multicellular spheroids show three-dimensional (3D) organization with extensive cell–cell and cell–extracellular matrix interactions. Owing to their native tissue-mimicking characteristics, mesenchymal stem cell (MSC) spheroids are considered promising as implantable therapeutics for stem cell thera...

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Bibliographic Details

Published in:	Cells
Main Authors:	Li-Chi Chen, Hsin-Wen Wang, Chieh-Cheng Huang
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	mesenchymal stem cells cell therapy 3D cell spheroids immunomodulation metabolic reconfiguration
Online Access:	https://www.mdpi.com/2073-4409/10/10/2747