SARS-CoV-2 Omicron Specific Mutations Affecting Infectivity, Fusogenicity, and Partial TMPRSS2-Independency

The COVID-19 pandemic resulted from the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since its first appearance in 2019, new SARS-CoV-2 variants of concern (VOCs) have emerged frequently, changing the infection’s dynamic. SARS-CoV-2 infects cells via two distinc...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Romano Strobelt, Karin Broennimann, Julia Adler, Yosef Shaul
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Subjects:	omicron functional mutants SARS-CoV-2 mutants viral-mediated membrane fusion lenti-Spike pseudovirus TMPRSS2 in viral infection SARS-CoV-2 endosomal infection
Online Access:	https://www.mdpi.com/1999-4915/15/5/1129