Expression changes of ER, PR, HER2, and Ki-67 in primary and metastatic breast cancer and its clinical significance

ObjectiveTo explore the altered expression of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and cell proliferation index (Ki-67) in primary and metastatic breast cancer lesions and the correlation between the primary tumor size, lymph node metas...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Xueyang Hu, Wenjun Chen, Fanfan Li, Pengfei Ren, Hongyang Wu, Congjun Zhang, Kangsheng Gu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Subjects:	breast tumor tumor metastasis heterogeneity prognosis DFS = disease-free survival
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1053125/full