Immunoinformatics and structural aided approach to develop multi-epitope based subunit vaccine against Mycobacterium tuberculosis

Abstract Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis (Mtb), which is one of the prominent reasons for the death of millions worldwide. The bacterium has a substantially higher mortality rate than other bacterial diseases, and the rapid rise of drug-resistant stra...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Guneswar Sethi, Rinku Polachirakkal Varghese, Avinash Kant Lakra, Subhashree Subhasmita Nayak, Ramadas Krishna, Jeong Ho Hwang
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-07-01
Subjects:	Mycobacterium tuberculosis Multi-epitope vaccine Docking Molecular dynamics simulation In silico cloning
Online Access:	https://doi.org/10.1038/s41598-024-66858-5