Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing

Background: Esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis and occurs with high frequency in China. The germline mutation profile in ESCC remains unclear, and therefore, the discovery of oncogenic alterations in ESCC is urgently needed. This study investigates the germli...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Jiaying Deng, Xiaoling Weng, Junyi Ye, Daizhan Zhou, Yun Liu, Kuaile Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Subjects:	whole exome sequencing ESCC germline mutation VUS clinical features
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00047/full