Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

Abstract Background Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathobiology remains poorly understood. We used Encyclop...

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Bibliographic Details
Published in:BMC Medical Genomics
Main Authors: Kerry E. Poppenberg, Kaiyu Jiang, Michael K. Tso, Kenneth V. Snyder, Adnan H. Siddiqui, John Kolega, James N. Jarvis, Hui Meng, Vincent M. Tutino
Format: Article
Language:English
Published: BMC 2019-10-01
Subjects:
Cell type
Cerebral aneurysm
Epigenetics
Genetics
Risk
Online Access:http://link.springer.com/article/10.1186/s12920-019-0591-7

Internet

http://link.springer.com/article/10.1186/s12920-019-0591-7

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