CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses

Modulation of metabolic pathways is linked to regulation of immune cells including macrophages. Here the authors identify a role for CD1d in the metabolic rewiring of macrophages, which alters responsiveness to innate stimuli.

Bibliographic Details
Published in:Nature Communications
Main Authors: Phillip M. Brailey, Lauren Evans, Juan Carlos López-Rodríguez, Anthony Sinadinos, Victoria Tyrrel, Gavin Kelly, Valerie O’Donnell, Peter Ghazal, Susan John, Patricia Barral
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Online Access:https://doi.org/10.1038/s41467-022-34532-x