Screening of immune cell activators from Astragali Radix using a comprehensive two-dimensional NK-92MI cell membrane chromatography/C18 column/time-of-flight mass spectrometry system

Astragali Radix (AR) is a clinically used herbal medicine with multiple immunomodulatory activities that can strengthen the activity and cytotoxicity of natural killer (NK) cells. However, owing to the complexity of its composition, the specific active ingredients in AR that act on NK cells are not...

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Bibliographic Details

Published in:	Journal of Pharmaceutical Analysis
Main Authors:	Xinyi Chai, Yanqiu Gu, Lei Lv, Chun Chen, Fei Feng, Yan Cao, Yue Liu, Zhenyu Zhu, Zhanying Hong, Yifeng Chai, Xiaofei Chen
Format:	Article
Language:	English
Published:	Elsevier 2022-10-01
Subjects:	NK cell activators Cell membrane chromatography Immunomodulatory herbal medicine Covalent bonding
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177922000491