Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections

Abstract Background Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function. To establish the efficacy of intramyocardial injections of an autologous UCB-MNC product at the time of stag...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Carlos Gallego-Navarro, James Jaggers, Harold M. Burkhart, Waldemar F. Carlo, David L. Morales, M. Yasir Qureshi, Joseph W. Rossano, Clinton E. Hagen, Drew K. Seisler, Susana Cantero Peral, Timothy J. Nelson
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Hypoplastic left heart syndrome Single ventricle Umbilical cord blood stem cell transplantation Mononuclear cells Stem cell Regenerative therapy
Online Access:	https://doi.org/10.1186/s13287-025-04316-3