Rho, ROCK and actomyosin contractility in metastasis as drug targets [version 1; referees: 2 approved]

Metastasis is the spread of cancer cells around the body and the cause of the majority of cancer deaths. Metastasis is a very complex process in which cancer cells need to dramatically modify their cytoskeleton and cope with different environments to successfully colonize a secondary organ. In this...

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Bibliographic Details

Published in:	F1000Research
Main Authors:	Irene Rodriguez-Hernandez, Gaia Cantelli, Fanshawe Bruce, Victoria Sanz-Moreno
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2016-04-01
Subjects:	Cancer Therapeutics Cell Adhesion Cell Growth & Division Cell Signaling Cytoskeleton Drug Discovery & Design Membranes & Sorting
Online Access:	http://f1000research.com/articles/5-783/v1