Aptamer-guided graphene oxide quantum dots for targeted suicide gene therapy in an organoid model of luminal breast cancer

Abstract Breast cancer is one of the most common cancers in women. One of the best therapeutic methods against breast cancer is gene therapy, while having an appropriate gene carrier is the biggest challenge of gene therapy. Hence, developing carriers with low cytotoxicity and high gene transfection...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Reza Taghizadeh-Tabarsi, Shiva Akbari-Birgani, Mehrnaz Amjadi, Soheila Mohammadi, Nasser Nikfarjam, Kosuke Kusamori
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Subjects:	Suicide gene therapy Graphen oxide quantum dot (GOQD) Luminal breast cancer Organoid model Gene delivery
Online Access:	https://doi.org/10.1038/s41598-024-74312-9