Cetuximab functionalized chitosan/hyaluronic acid-based nanoparticles loaded with cabazitaxel enhances anti-tumor efficacy in DMBA-induced breast cancer model in rats through spatial targeting

The article discusses the ionic gelation of cationic chitosan (CS) with anionic hyaluronic acid (HA) sodium salt to form nanoparticles in the range of 125 nm. The particles were further functionalized with cetuximab to endow it with the ability to spatially target the tumor over-expressing EGFR. Sol...

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書誌詳細

出版年:	Chemical Physics Impact
主要な著者:	Abhishek Jha, Pooja Goswami, Manish Kumar, Kanchan Bharti, Manjit Manjit, Amol P. Satpute, Ashutosh Gupta, Sudheer Moorkoth, Biplob Koch, Brahmeshwar Mishra
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-12-01
主題:	Chitosan Cabazitaxel Hyaluronic acid Cetuximab Breast cancer
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2667022424002949