Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer

IntroductionNext-generation sequencing (NGS) is currently widely used for biomarker studies and molecular profiling to identify concurrent alterations that can lead to the better characterization of a tumor’s molecular landscape. However, further evaluation of technical aspects related to the detect...

Full description

Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Sergi Clavé, Jennifer B. Jackson, Marta Salido, Jacob Kames, Kelly M. R. Gerding, Ellen L. Verner, Eric F. Kong, Elizabeth Weingartner, Joan Gibert, Max Hardy-Werbin, Pedro Rocha, Xènia Riera, Erica Torres, James Hernandez, Gustavo Cerqueira, Donna Nichol, John Simmons, Álvaro Taus, Lara Pijuan, Beatriz Bellosillo, Edurne Arriola
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	next generation sequencing (NGS) non-small cell lung cancer (NSCLC) MET amplification ALK rearrangement fluorescence in situ hybridization (FISH) biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1225646/full