Girolline is a sequence context-selective modulator of eIF5A activity

Abstract Natural products have a long history of providing probes into protein biosynthesis, with many of these compounds serving as therapeutics. The marine natural product girolline has been described as an inhibitor of protein synthesis. Its precise mechanism of action, however, has remained unkn...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nature Communications
المؤلفون الرئيسيون: Tilman Schneider-Poetsch, Yongjun Dang, Wakana Iwasaki, Mayumi Arata, Yuichi Shichino, Ali Al Mourabit, Celine Moriou, Daniel Romo, Jun O. Liu, Takuhiro Ito, Shintaro Iwasaki, Minoru Yoshida
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2025-01-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-024-54838-2