Macrophages facilitate coal tar pitch extract-induced tumorigenic transformation of human bronchial epithelial cells mediated by NF-κB.

OBJECTIVE: Chronic respiratory inflammation has been associated with lung cancer. Tumor-associated macrophages (TAMs) play a critical role in the formation of inflammation microenvironment. We sought to characterize the role of TAMs in coal tar pitch extract (CTPE)-induced tumorigenic transformation...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Feifei Feng, Yiming Wu, Shaofeng Zhang, Yu Liu, Lijuan Qin, Yongjun Wu, Zhen Yan, Weidong Wu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3515562?pdf=render