Endothelial cells express NKG2D ligands and desensitize antitumor NK responses

Natural Killer (NK) cells confer protection from tumors and infections by releasing cytotoxic granules and pro-inflammatory cytokines upon recognition of diseased cells. The responsiveness of NK cells to acute stimulation is dynamically tuned by steady-state receptor-ligand interactions of an NK cel...

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Bibliographic Details

Published in:	eLife
Main Authors:	Thornton W Thompson, Alexander Byungsuk Kim, P Jonathan Li, Jiaxi Wang, Benjamin T Jackson, Kristen Ting Hui Huang, Lily Zhang, David H Raulet
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2017-12-01
Subjects:	Natural killer cells endothelial cells NKG2D
Online Access:	https://elifesciences.org/articles/30881