Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

TRAIL (TNF-related apoptosis-inducing ligand) is a potent inducer of tumor cell apoptosis through TRAIL receptors. While it has been previously pursued as a potential anti-tumor therapy, the enthusiasm subsided due to unsuccessful clinical trials and the fact that many tumors are resistant to TRAIL....

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:eLife
المؤلفون الرئيسيون: Yin Luo, Huanmeng Hao, Zhangjie Wang, Chih Yean Ong, Robert Dutcher, Yongmei Xu, Jian Liu, Lars C Pedersen, Ding Xu
التنسيق: مقال
اللغة:الإنجليزية
منشور في: eLife Sciences Publications Ltd 2024-01-01
الموضوعات:
الوصول للمادة أونلاين:https://elifesciences.org/articles/90192