<i>Streptococcus pyogenes</i> NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O

Necrotizing soft tissue infections caused by <i>Streptococcus pyogenes</i> (group A streptococcus [GAS]) are characterized by rapid and extensive necrosis of fascia and muscle. Molecular epidemiological studies have demonstrated a positive correlation between GAS isolates that cause inva...

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Bibliographic Details
Published in:Microorganisms
Main Authors: Eric R. McIndoo, Emily Price, Cheri L. Lamb, Christopher S. Dayton, Clifford R. Bayer, Dennis L. Stevens, Amy E. Bryant, Sarah E. Hobdey
Format: Article
Language:English
Published: MDPI AG 2022-07-01
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Online Access:https://www.mdpi.com/2076-2607/10/7/1476