Asiatic acid inhibits HBV cccDNA transcription by promoting HBx degradation

Abstract Background Hepatitis B virus (HBV) infection is a persistent global public health problem, and curing for chronic hepatitis B (CHB) through the application of existing antiviral drugs is beset by numerous challenges. The viral protein HBx is a critical regulatory factor in the life cycle of...

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Bibliographic Details

Published in:	Virology Journal
Main Authors:	Ranran Li, Chunduo Wang, Kexin Xu, Zongzhu Zhan, Siyi He, Jihua Ren, Fan Li, Nana Tao, Zhihong Li, Zhen Yang, Haibo Yu
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Asiatic acid HBx Hepatitis B virus
Online Access:	https://doi.org/10.1186/s12985-024-02535-3