The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation

The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic properties. The microparticles were prepared from ethanol/water solutions containing bosentan using spray dryer. Three types of formulations (SD...

詳細記述

書誌詳細

出版年:	Pharmaceutics
主要な著者:	Yong-Bin Kwon, Ji-Hyun Kang, Chang-Soo Han, Dong-Wook Kim, Chun-Woong Park
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2020-08-01
主題:	bosentan inhalable dry powder surface morphology roughness physicochemical properties aerodynamic properties
オンライン･アクセス:	https://www.mdpi.com/1999-4923/12/8/765