Delayed Gut Colonization Changes Future Insulin Resistance and Hepatic Gene Expression but Not Adiposity in Obese Mice

Objective. The importance of early microbial dysbiosis in later development of obesity and metabolic disorders has been a subject of debate. Here we tested cause and effect in mice. Methods. Germ-free male Swiss Webster mice were colonized in a specific-pathogen-free (SPF) facility at 1 week (1W) an...

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Bibliographic Details
Published in:Journal of Obesity
Main Authors: Maria B. B. Ebert, Caroline M. J. Mentzel, Anders Brunse, Lukasz Krych, Camilla H. F. Hansen
Format: Article
Language:English
Published: Wiley 2024-01-01
Online Access:http://dx.doi.org/10.1155/2024/5846674