The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme

Pseudorabies virus (PRV) DNA replication occurs in the nuclei of infected cells and requires the viral DNA polymerase. The PRV DNA polymerase comprises a catalytic subunit, UL30, and an accessory subunit, UL42, that confers processivity to the enzyme. Its nuclear localization is a prerequisite for i...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Yi-Ping eWang, Wen-Juan eDu, Li-Ping eHuang, Yan-Wu eWei, Hong-Li eWu, Li eFeng, Chang-Ming eLiu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-02-01
Subjects:	DNA polymerase pseudorabies virus nuclear transport Accessory subunit UL42
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00124/full