Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41

Given the high variability and drug-resistance problem by human immunodeficiency virus type 1 (HIV-1), the development of bispecific or multi-specific inhibitors targeting different steps of HIV entry is highly appreciated. We previously generated a very potent short-peptide–based HIV fusion inhibit...

全面介紹

書目詳細資料

發表在:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Hongxia Yan, Tong Wu, Yue Chen, Hongliang Jin, Li Li, Yuanmei Zhu, Huihui Chong, Yuxian He
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2022-05-01
主題:	HIV entry bispecific inhibitor fusion inhibitors CD4 ibalizumab
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.916487/full