L-Asparaginase from <i>Penicillium sizovae</i> Produced by a Recombinant <i>Komagataella phaffii</i> Strain

L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential amino acid synthesized by normal cells, but not by neoplastic cells. Adverse effects of L-asparaginase formulations are asso...

Full description

Bibliographic Details
Published in:Pharmaceuticals
Main Authors: Marcela Freitas, Paula Souza, Mauricio Homem-de-Mello, Yris M. Fonseca-Bazzo, Damaris Silveira, Edivaldo X. Ferreira Filho, Adalberto Pessoa Junior, Dipak Sarker, David Timson, João Inácio, Pérola O. Magalhães
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Subjects:
L-asparaginase
acute lymphoblastic leukemia
cloning
expression
<i>Penicillium sizovae</i>
<i>Komagataella phaffii</i>
Online Access:https://www.mdpi.com/1424-8247/15/6/746

Internet

https://www.mdpi.com/1424-8247/15/6/746

Similar Items