A reciprocal relationship between mitochondria and lipid peroxidation determines the chondrocyte intracellular redox environment

In orthopedic research, many studies have applied vitamin E as a protective antioxidant or used tert-butyl hydroperoxide to induce oxidative injury to chondrocytes. These studies often support the hypothesis that joint pathology causes oxidative stress and increased lipid peroxidation that might be...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Madeline R. Hines, Piedad C. Gomez-Contreras, Suryamin Liman, Alexandria M. Wilson, Kevin J. Lu, Jaycie A. O'Neill, Jacob S. Fisher, Douglas C. Fredericks, Brett A. Wagner, Garry R. Buettner, Holly Van Remmen, Mitchell C. Coleman
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	Lipid peroxidation Glutathione peroxidase 4 Mitochondria Cartilage Chondrocyte Immuno-spin trapping
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231724002842