Design and application of artificial rare L-lysine codons in Corynebacterium glutamicum

Background: L-lysine is widely used in the feed, food, and pharmaceutical industries, and screening for high L-lysine-producing strains has become a key goal for the industry.Methods: We constructed the rare L-lysine codon AAA by corresponding tRNA promoter replacement in C. glutamicum. Additionally...

Full description

Bibliographic Details
Published in:Frontiers in Bioengineering and Biotechnology
Main Authors: Cuiping Yang, Zehao Peng, Lu Yang, Bowen Du, Chuanzhuang Guo, Songsen Sui, Jianbin Wang, Junlin Li, Junqing Wang, Nan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Subjects:
Corynebacterium glutamicum
gene knockout
rare codon
L-lysine
high flux
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1194511/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1194511/full

Similar Items