FOXP3+ Treg cells and its gender bias in autoimmune diseases

CD4+CD25+ Regulatory T (Treg) cells play a pivotal role in the maintenance of immune homeostasis, where the X-linked master transcription factor Forkhead box P3 (FOXP3) determines Treg cell development and function. Genetic deficiency of Foxp3 induces dysfunction of Treg cells and immuno-dysregulati...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Jia eNie, Yangyang eLi, Guo Song Zheng, Andy eTsun, Bin eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Subjects:
Autoimmunity
Inflammation
Foxp3
Gender difference
Treg cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00493/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00493/full

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